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Consumer Products Review has asked several skin care professionals to compare and rank the hottest anti-wrinkle and anti-aging creams on the market.  After reviewing several top products and brands, we have narrowed the field down to four excellent anti wrinkle cream products.  Results are available here to help you make the best decision for your needs.

Common Wrinkle Cream Ingredients

Vitamin A (retinol)
Retinol is a vitamin A derivative and is the first antioxidant to be widely used in OTC anti wrinkle creams. Antioxidants are substances that neutralize free radicals — unstable oxygen molecules that break down skin cells and cause wrinkles. Retinol is less potent than the vitamin A derivative tretinoin, the only prescription topical treatment approved by the Food and Drug Administration for treating wrinkles. Both retinol and tretinoin can cause redness and irritation, but retinol's side effects are usually milder.

Hydroxy acids
Alpha hydroxy acids, beta hydroxy acids and poly hydroxy acids are all synthetic versions of acids derived from sugar-containing fruits. These acids often used in anti wrinkle creams, are exfoliants, substances that remove the upper layer of old, dead skin and stimulate the growth of smooth, evenly pigmented new skin.

Alpha-lipoic acid (ALA)
Alpha-lipoic acid is an antioxidant that penetrates skin cell membranes and is often an ingredient in anti wrinkle creams, where it neutralizes free radicals and increases the effectiveness of other antioxidants such as vitamins C and E. It may also work as a superficial chemical peel to exfoliate dead skin and reduce the appearance of wrinkles.

Coenzyme Q-10
Coenzyme Q-10 is a nutrient that helps regulate energy production in cells. This is very commonly used in anti wrinkle creams.

Copper peptides
Copper is a trace element found in every cell. In topical products, it's combined with small protein fragments called peptides. Copper peptides enhance wound healing. They also stimulate production of collagen and may enhance the action of antioxidants.

Growth factors
Growth factors are naturally occurring hormones found in plants and animals. This is a main ingredient in anti wrinkle creams. They act as chemical messengers between cells. Kinetin, a plant growth factor, is the one most often used in cosmetics.

Soy isoflavones
Protein extracts of soybean and soymilk contain several different estrogen-like substances called isoflavones. Because they may mimic the effects of estrogen, they're sometimes called phytoestrogens. Phytoestrogens may produce wrinkle-reducing effects on skin that are similar to those resulting from hormone therapy.

Tea extracts
Green, black and oolong tea contain compounds with antioxidant and anti-inflammatory properties. Green tea extracts are the ones most commonly found in wrinkle creams.

Vitamin C
Vitamin C is an antioxidant nutrient that helps recycle vitamin E. It also promotes collagen formation.

Vitamin E
Vitamin E, an antioxidant nutrient, is the major antioxidant found in human skin. Declining levels in skin are associated with wrinkles. This is a very common substance in anti wrinkle creams.

Product Comparisons

Our Wrinkle Cream CPR Rating is based on several factors listed below:
  • Effectiveness
  • Reputation
  • Support
  • Guarantee
  • Price
  • Consumer reports
A composite score using weighted averages is computed and then converted to our 5-star CPR Rating System. Five stars represent the highest rating. Only anti wrinkle cream products rating 3 stars or better are reported.


The active ingredient in Avotone, Acetyl Hexapeptide-3 (Argireline), has been proven to reduce the depth of the wrinkles in the face caused by the contraction of the muscles by facial expression, especially around the eyes and the forehead.
cpr rating
one bottle  $89.95
with discount $53.31 (x3 bottles)
additional bonus free shipping
guarantee 60 days
website click here


Revitol Complete is a cutting edge anti wrinkle cream solution which can help you look younger and more beautiful by reducing the appearance of wrinkles, fine lines and other effects of aging. This revolutionary anti-wrinkle cream utilizes the most advanced ingredients available today

cpr rating
one bottle $59.95
one pack $99.95 (moisturizer & serum)
with discount $66.65 (x3 packs)
guarantee 90 days
website click here

Stri-Vectin SD® 6 oz.

Stri-Vectin SD

After reviewing and verifying the clinical data, researchers noted an incredible 93% of subjects demonstrated a measurable reduction in the appearance of stretch marks. The same active ingredients when used on the face have been shown to diminish fine lines, wrinkles and crow's feet.

cpr rating
one bottle $135.00
with discount $128.25 (x3 bottles)
additional bonus free shipping
guarantee 30 days
website click here

OHT Peptide-3

Peptides play a vital role in the skin's healing process. These protein molecules, found naturally in the body, send out signals when damaged skin is in need of repair. OHT Peptide-3 anti wrinkle cream contains three patented peptides that target both upper and lower layers of the skin, helping to reduce wrinkles and repairing stretch marks.

cpr rating
one bottle $114.99
with discount $99.99 (Refills with AutoShip)
additional bonus none
guarantee 30 days
website click here

Explanation of attributes

The one bottle anti wrinkle cream price is the price if buying only a one bottle. The one bottle supply price with discount is the price when purchasing several bottles (required order quantity is specified in parentheses). Some manufacturers offer an additional bonus if placing a large order. The number of days for their guarantee varies. The anti wrinkle cream product's website offers more information and order taking.

Editor's Choice

Our testing and reports from consumers like you have resulted in 5-star ratings for Avotone anti wrinkle cream. The exceptional rating was justified not only by the product and value, but also by excellent customer service and strong reputation for reliability.

For more information on anti wrinkle cream or to place an order click here to continue.

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